Analysis of Viscous Fluid Flow in Micropump Elements for Circulatory Support Systems

The paper presents the results of developing a micro-pump for the circulatory support system. The maximum diameter of the micropump is 6.5 mm. This allows it to be introduced into the human body through the femoral artery, which ensures its minimally invasive use. The micropump draws blood from the left ventricle of the heart and pumps it into the aorta behind the aortic valve. The numerical analysis of the spatial flow of an incompressible viscous fluid (blood) in the developed elements of the micropump allowed us to prove that its flow path corresponds to the conditions of minimal hemolysis and thrombosis during blood pumping. The developed micropump ensures uniform distribution of pressure and blood flow velocity at the outlet, which guarantees a uniform blood supply to the aorta. There are no zones of stagnation of blood and vortices throughout the flow part of the micropump, which reduces thrombosis in the micropump. In the entire volume of blood flow, even in the peripheral section of the micropump impeller, shear rates and shear stresses do not exceed critical values, which leads to minimal blood hemolysis in the developed elements of the micropump. The obtained results of 3D flow simulation in the elements of the micropump made it possible to develop design documentation for the manufacture and testing of its prototype on hydraulic and hemodynamic stands

This work was supported by the Fund for the Promotion of Innovations (сontract no. 3052GS1/44987 dated 04.06.2019)

References

[1] Shumakov V.I., Tolpekin V.E., Melimuka I.V., et al. Diagrams of spatula pumps implantation for circulatory support. Grudnaya khirurgiya, 1992, no. 11-12, pp. 3--6 (in Russ.).

[2] Shumakov V.I., Tolpekin V.E., Romanov O.V., et al. Axial-flow micropumped system of assisted circulation. Biomed. Eng., 1994, vol. 28, no. 5, pp. 231--233. DOI: https://doi.org/10.1007/BF00556681

[3] Khaustov A.I. Nasosy dlya sistem vspomogatel’nogo krovoobrashcheniya [Pumps for circulatory support systems]. Moscow, MAI Publ., 2008.

[4] Chernyavskiy A., Fomichev A., Ruzmatov T., et al. Long-term biventricular support following myocardial infarction from anterior descending coronary artery damage due to stabbing: a case report. J. Card. Surg., 2020, vol. 35, no. 9, pp. 2422--2424. DOI: https://doi.org/10.1111/jocs.14816

[5] Giridharan G.A., Lee T.J., Ising M., et al. Miniaturization of mechanical circulatory support systems. Artif. Organs, 2012, vol. 36, no. 8, pp. 731--759. DOI: https://doi.org/10.1111/j.1525-1594.2012.01523.x

[6] Boyarskiy G.G., Sorokin A.E., Khaustov A.I. Experimental pressure-flow characteristics determining of micropumps for orbital station biotechnical system. Vestnik MAI [Aerospace MAI Journal], 2019, vol. 26, no. 4 (in Russ.).DOI: https://doi.org/10.34759/vst-2019-4-184-190

[7] Khaustov A.I. Theoretical and experimental investigations of pumps for pressure systems of aerospace vehicles. Vestnik MAI [Aerospace MAI Journal], 2008, vol. 15, no. 1 (in Russ.). Available at: http://vestnikmai.ru/publications.php?ID=7664

[8] Khaustov A.I., Shashkin I.N., Kindeev M.I. Design of axial flow pumps for thermoregulation systems of aircraft. Trudy MAI, 2012, no. 50 (in Russ.). Available at: http://trudymai.ru/published.php?ID=28698

[9] Dmitrieva O.Yu., Buchnev A.S., Drobyshev A.A., et al. Hemolysis research of implantable axial flow pump for two-step heart transplantation in children. Vestnik transplantologii i iskusstvennykh organov [Russian Journal of Transplantology and Artificial Organs], 2017, vol. 19, no. 1, pp. 22--27 (in Russ.). DOI: https://doi.org/10.15825/1995-1191-2017-1-22-27

[10] Wang S., Tan J., Yu Z. Shear stress and hemolysis analysis of blood pump under constant and pulsation speed based on a multiscale coupling model. Math. Probl. Eng., 2020, vol. 2020, art. 8341827. DOI: https://doi.org/10.1155/2020/8341827

[11] Belotserkovskiy O.M. Chislennoe modelirovanie v mekhanike sploshnykh sred [Numerical modeling in continuum mechanics]. Moscow, FIZMATLIT Publ., 1984.

[12] Anderson D.A., Tannehill J.C., Pletcher R.H. Computational fluid mechanics and heat transfer. McGraw-Hill, 1984.

[13] Krasnikov G.E., Nagornov O.V., Starostin N.V. Modelirovanie fizicheskikh protsessov s ispol’zovaniem paketa Comsol Multiphysics [Modeling physical processes using Comsol Multiphysics package]. Moscow, NIYaU MIFI Publ., 2012.

[14] Gerasimenko T.N., Kindeeva O.V., Petrov V.A., et al. Modelling and characterization of a pneumatically actuated peristaltic micropump. Appl. Math. Model., 2017, vol. 52, pp. 590--602. DOI: https://doi.org/10.1016/j.apm.2017.08.008

[15] Khaustov A.I., Tolpekin V.E., Gavrilyuk V.N., et al. Modeling the viscous liquid flow in 3D channels. Doklady Akademii Nauk RF, 1998, vol. 358, no. 6, pp. 1--4 (in Russ.).